II – Show by chemical equation the following conversions  :              (10 marks)

1.       Serine a . a to pyruvic acid .

2.       Guanido acetate to creatine phosphate .

3.       Glycine to glychocholic acid .

4.       Cysteine to cystine .

5.       Homogentisic acid to maleylacetoacetic acid .

III – Choose the correct answer :                                                         (2 ½ marks )

1-Most of the ammonia is derivatized and transported in the blood as ?

(A) glutamate        (B) arginine      (C) glutamine       (D) alanine .

2-An amino acid which is strictly ketogenic will be able to yeild ?

     (A) Energy       (B) ketone bodies     (C) Fatty acids       (D) Glucose .

3-Creatinine is formed from the ?

          (A) oxidation of protein          (B) deamination of dibasic amino acid

          (C) oxidation of creatine         (D) metabolism of purines .

4-Which enzyme deficiency is responsible for phenylketonuria ( PKU )?

        (A) p-hydroxyphenyl pyruvic hydroxylase (B) phenyl alanine hydoxylase

   (C) Tyrosine transaminase                   (D) Homogentisic acid oxidase .

 5-The reaction of urine in convertion is   ?

          (A)Neutral                     (B) Alkaline                 (C) Acidic .   (D) Basic

IV – Tick (?   ) or ( X )  and correct the wrong answers:                  ( 2 ½ marks )

1.       The consistency of urine in equines is watery .

2.       Chronic liver diseases cause pathological glycosuria .

3.       The odour of freshly voided urine is due to volatile organic acids .

4.       Transamination reaction requires Biotin as a co factor .

5.       carbamoyl phosphate synthetase I is cytosolic enzyme .

                                               Good Luck       Prof.Dr. Ibrahim Fattouh