14/5/2015
Delayed wound healing is a
major complication of diabetes because the physiological changes in tissues and
cells impair the wound healing process. This can result in additional disease
outcomes such as diabetic foot ulcer, a significant cause of morbidity in the
growing population of diabetic patients. A new study has found that topically
applied simvastatin accelerates wound healing in diabetic mice, suggesting
important implications for humans with diabetes.
This study is published in the December issue of The American Journal of Pathology.
The research was performed by scientists at the Departments of
Dermatology and Ophthalmology of Kyoto Prefectural University School of
Medicine, Kyoto, Japan; the Department of Dermatology at Hamamatsu University
School of Medicine, Hamamatsu, Japan; and Shiseido Innovative Scientific
Research Center, Yamamoto, Japan.