الابحاث

Publications

Publications in international journals

11- Mahmoud Kandeel. Efficacy of amprolium and toltrazuril in chicken with subclinical infection of cecal coccidiosis.  Indian Journal of Pharmacology. In press.

10- Mahmoud Kandeel and Yukio Kitade. Binding dynamics and energetic insight into the molecular forces driving nucleotide binding by guanylate kinase. Journal of Molecular Recognition. 24(2):322-332 March-April 2011

9- Mahmoud Kandeel and Yukio Kitade. The substrate binding preferences of Plasmodium thymidylate kinase. Biological and Pharmaceutical Bulletin. 34:173-176. January 2011

8- Mahmoud Kandeel and Yukio Kitade. Substrate specificity and nucleotides binding propertiesof NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum. Journal of Bioenergetics and Biomembranes. 42:361-369. October 2010

7-Mahmoud Kandeel, Yoshiaki Kitamura and Yukio Kitade. The exceptional properties of Plasmodium deoxyguanylate as potential area for metabolic and drug discovery studies. Nucleic Acids Symposium Series. (Oxford) 53:39-40. October 2009

6-Mahmoud Kandeel, Aya Kato and Yukio Kitade. Thymidylate kinase: The lost chemotherapeutic target. Nucleic Acids Symposium Series. (Oxford) 53:283-284. October 2009

5-Mahmoud Kandeel, Tatsuya Miyamoto and Yukio Kitade. Bioinformatics, enzymologic properties, and comprehensive tracking of Plasmodium falciparum nucleoside diphosphate kinase. Biological and Pharmaceutical Bulletin. 32(8):1321-1327. August 2009

4- Mahmoud Kandeel, Takayuki Ando, Yoshiaki Kitamura, Magdi Abdel-Aziz and Yukio Kitade. Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery. Parasitology 136 (1): 11-25. January 2009

3- Mahmoud Kandeel and Yukio Kitade. Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase. Journal of Biochemistry. 144 (2): 245-250. August 2008

2- Mahmoud Kandeel, Masayuki Nakanishi, Takayuki Ando, Kamal El-Shazly, Tarek Yosef, Yoshihito Ueno and Yukio Kitade. Molecular cloning, expression, characterization and mutation of Plasmodium falciparum guanylate kinase. Molecular and Biochemical Parasitology. 159 (2): 130-133. June 2008

1- Takayuki Ando, Hisashi Shinohara, Xiong Luo, Mahmoud Kandeel and Yukio Kitade. Facile synthesis of 1',2'-cis-beta-pyranosyladenine nucleosides. Carbohydrate Research. 342 (17): 2641-2648. December 2007

Publications in local journals and presentations

8- Mahmoud Kandeel and Yukio Kitade. Genomic, proteomic and molecular model analyses of TMP kinase from some blood-parasitic protozoa.  One-step forward in development of broad spectrum antiprotozoal drugs. Kafr El-Sheikh Veterinary Medical Journal. 3 (1): 734 – 745. May 2009

7- Magdi Abdel-Aziz, Kamal El-Shazly and Mahmoud Kandeel. Comparative efficacy of diclazuril and semduramicin in chickens infected with E. tenella. Kafr El-Sheikh Veterinary Medical Journal. 1 (1): 587-609. April 2003

6- Aya Kato, Mahmoud Kandeel, Takayuki Ando, Yoshiaki Kitamura, Yukio Kitade The discovery and synthesis of thymidine monophosphate kinase inhibitors as a new antimalaria drugs. The malaria forum, Matsuyama, Japan, 2008, Page 17.

5- Mahmoud Kandeel, Aya Kato, Takayuki Ando, Masayuki Nakanishi, Yukio Kitade. Cloning and enzymologic characterization of Plasmodium falciparum guanylate kinase. The annual meeting of the Japanese pharmaceutical society, 2008, page 63

4- Mahmoud Kandeel and Yukio Kitade. Plasmodium falciparum Guanosine Monophosphate Kinase:A New Target for the Development of Anti-Malarial Drugs. Proceedings of the First Egypt-Japan International Symposium on Science and Technology (EJISST2008) June 8~10, 2008 – WASEDA University, Tokyo, Japan

3- Mahmoud Kandeel. World Health development, 7th Global Conference on Human Development, Hida-Takayama, Japan. 17-21/11/2008

2- Mahmoud Kandeel. Genomic, proteomic and molecular model analyses of TMP kinase from some blood-parasitic protozoa.  One-step forward in development of broad spectrum antiprotozoal drugs. The third Kafr El-Sheikh Veterinary Medical conference

1- Mahmoud Kandeel. Comparative efficacy of diclazuril and semduramicin in chickens infected with E. tenella. The first Kafr El-Sheikh Veterinary Medical

conference